Vol. 20 No. 2 (2022)
An Approach To:

Approach to Acid Base Abnormalities

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  • Tharaniya Vallipuram
Tharaniya Vallipuram
McGill
lemons
DOI: https://doi.org/10.26443/mjm.v20i2.885

Published 2022-07-05

Keywords

  • acidosis,
  • alkalosis

How to Cite

1.
Vallipuram T. Approach to Acid Base Abnormalities . McGill J Med [Internet]. 2022 Jul. 5 [cited 2025 Oct. 30];20(2). Available from: https://mjm.mcgill.ca/article/view/885

Copyright (c) 2022 Tharaniya Vallipuram

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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Abstract

This Approach To article provides an overview on acid-base imbalance, with a particular focus on metabolic acidosis. It provides a general step-wise approach on how to determine what acid-base imbalance is occurring and some of the potential underlying causes for each. 

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References

  1. References
  2. Clinical laboratory tests – Adult normal values [Internet]. Medical Council of Canada. Medical Council of Canada; 2020 [cited 2021Mar29]. Available from: https://mcc.ca/objectives/normal-values/
  3. Acid-base disorders [Internet]. Amboss. Amboss; 2021 [cited 2021Mar29]. Available from: https://next.amboss.com/us/article/zL0rZS?q=acid-base+disorders#sRctoX0
  4. Rennke HG, Denker BM. In: Acid-Base Physiology and Metabolic Alkalosiss. 4th ed. Baltimore, MD: Lippincott Williams & Wilkins; 2014. p. 124–52.
  5. Kaufman DA. [Internet]. Interpretation of Arterial Blood Gases (ABGs). American Thoracic Society; [cited 2021Mar29]. Available from: https://www.thoracic.org/professionals/clinical-resources/critical-care/clinical-education/abgs.php
  6. Emmett M, Palmer BF. Simple and mixed acid-base disorders [Internet]. UpToDate. Wolters Kluwer; 2020 [cited 2021Mar29]. Available from: https://www.uptodate.com/contents/simple-and-mixed-acid-base-disorders?search=acid+base+disturbances&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1
  7. Danziger J, Zeidel M, Parker MJ. In: Maintaining the serum pH: Acid Base Balance. Baltimore, MD: Lippincott Williams & Wilkins; 2012. p. 155–77.
  8. Emmet M, Palmer BF. The delta anion gap/delta HCO3 ratio in patients with a high anion gap metabolic acidosis [Internet]. UptoDate. Wolters Kluwer; 2020 [cited 2021Mar29]. Available from: https://www.uptodate.com/contents/the-delta-anion-gap-delta-hco3-ratio-in-patients-with-a-high-anion-gap-metabolic-acidosis#H1100297057
  9. Agabegi SS, Agabegi ED, Chuang K, Duncan MD. Acid Base Disorders. In: Step-up to medicine. 4th ed. Philadelphia: Wolters Kluwer; 2016. p. 319–24.
  10. Emmett M, Szerlip H. Approach to the adult with metabolic acidosis [Internet]. UpToDate. Wolters Kluwer; 2020 [cited 2021Mar29]. Available from: https://www.uptodate.com/contents/approach-to-the-adult-with-metabolic-acidosis?search=mudpiles&source=search_result&selectedTitle=1~32&usage_type=default&display_rank=1#H1585357
  11. Kovesdy C. Pathogenesis, consequences, and treatment of metabolic acidosis in chronic kidney disease [Internet]. UpToDate. Wolters Kluwer; 2021 [cited 2021Mar29]. Available from: https://www.uptodate.com/contents/pathogenesis-consequences-and-treatment-of-metabolic-acidosis-in-chronic-kidney-disease#H2
  12. Ghimire P, Dhamoon AS. Ketoacidosis. [Updated 2020 Nov 21]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK534848/
  13. Boyer E, Weibrecht K. Salicylate (aspirin) poisoning in adults [Internet]. UpToDate. Wolters Kluwer; 2020 [cited 2021Mar29]. Available from: https://www.uptodate.com/contents/salicylate-aspirin-poisoning-in-adults?search=mudpiles&topicRef=2291&source=related_link#H8
  14. Le T, Bhushan V, Deol M, Reyes G. Acidosis and Alkalosis . In: First aid for the USMLE Step 1. New York: McGraw-Hill Education; 2021. p. 616.