Vol. 7 No. 1 (2003)
Letter to the Editor

TRANSIENT INHIBITION OF SMAD1/SMAD4 TRANSLATION USING ANTISENSE OLIGODEOXYNUCLEOTIDES IN VITRO

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  • Waël C. Hanna ,
  • Indra R. Gupta
DOI: https://doi.org/10.26443/mjm.v7i1.623

Published 2020-12-01

Keywords

  • fetal development,
  • primitive kidney

How to Cite

1.
Hanna WC, Gupta IR. TRANSIENT INHIBITION OF SMAD1/SMAD4 TRANSLATION USING ANTISENSE OLIGODEOXYNUCLEOTIDES IN VITRO. McGill J Med [Internet]. 2020 Dec. 1 [cited 2025 Oct. 24];7(1). Available from: https://mjm.mcgill.ca/article/view/623
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References

  1. De Vries, L., Zheng, B., Fischer, T., Elenko, E., and Farquhar, M. (2000) The Regulator of G-protein signalling family. Annu. Rev. Pharmacol. Toxicol. 40, 235-271
  2. Panetta, R., Guo, Y., Magder, S. and Greenwood, M. T. (1999) Regulators of G-protein signalling (RGS) 1 and 16 are induced in response to bacterial lipopolysacchiride and stimulate c-fos promoter expression. Biochem. Biophys. Res. Commun. 259, 550-556
  3. Grant, S. L., Lassegue, B., Griendling, K. K., Fukai, M. U., Lyons, P. R. and Alexander, R. W. (2000) Specific regulation of RGS2 messenger RNA by Angiotensin II in cultured vascular smooth muscle cells. Molec. Pharmacology, 57, 460-467.
  4. Fong, C. W., Zhang, Y., Neo, S. Y., and Lin, S. C. (2000) Specific induction of RGS16 mRNA by protein kinase C in CEM leukaemia cells is mediated via tumour necrosis factor a in a calcium-sensitive manner. Biochem. J., 352, 747-753
  5. Chen, C., Zheng, B., Han, J., and Lin, S.-C. (1997) Characterization of a novel mammalian RGS protein that binds to Ga proteins and inhibits pheromone signalling in yeast. J. Biol. Chem. 272, 8679-8885
  6. Tamirisa, P., Blumer, K. J., Muslin, A. J. (1998) RGS4 Inhibits G-protein Signaling in Cardiomyocytes. Circulation, 99, 441- 447
  7. Limbird, L. E., and Vaughan, D. E. (1999) Augmenting b receptors in the heart: Short-term gains offset by long term pains? Proc. Natl. Acad. Sci. 96, 7125-7127
  8. Zhang, S., Watson, N., Zahner, J., Rottman, J. N., Blumer, K. J., and Muslin, A. J. (1998) RGS3 and RGS4 are G-protein inhibitors in the heart. J. Mol. Cell Cardiol. 30, 269-276
  9. Owen, V. J., Burton, B. J., Mullen, A. J., Birks, E. J., Barton, P., and Yacoub, M. H., (2001) Expression of RGS3, RGS4 and Gi alpha 2 in acutely failing donor hearts and end-stage heart failure.
  10. European Heart Journal, 22, 1025-1020
  11. Kong, Janice (2001) Master of Science (MSc) Thesis, McGill University.
  12. Rogers, J. H., Tsirka, A., Kovacs, A., Blumer, J. K., Dorn, G. W., Muslin, A. J. (2001) RGS4 reduces contractile dysfunction and hypertrophic gene induction in Gaq overexpressing mice. J. Mol. Cell Cardiol. 33, 209-218
  13. http://www.ncbi.nlm.nih.gov/Genbank/index.html
  14. Greenwood M.T., Hukovic, N., Kumar, U., Panetta, R., Hjorth, S.A., Srikant, C.B., Patel, Y.C. (`997) Ligand binding pocket of the human somatostatin receptor 5: mutational analysis of the extracellular domains. Mol. Pharmacol. 52, 807-814
  15. Greenwood, M.T., Guo, Y., Kumar, U., Beausejours, S., Hussain, S.N. (1997) Distribution of protein inhibitor of neuronal nitric oxide synthase in rat brain. Biochem. Biophys. Res. Commun. 238, 617-621
  16. Mumberg, D., Muller, R., and Funk, M. (1994) Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression. Nucleic Acids Res. 22, 5767-5768
  17. Dohlman, H. G., Song, J., Ma, D., Courchesne, W. E., and Thorner, J. (1996) SSt2, a Negative regulator of pheromone signalling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein a subunit) Mol. Cell. Biol. 16, 5194-5209
  18. Gietz, D., St Jean, A., Woods, R. A. , Schiestl, R. H. (1992) Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20, 1425
  19. Druey, K. M., Blumer, K. J., Kang, V. H., Kehrl, J. H. (1996) Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family. Nature. 379, 742-746