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Narrative Review

Vol. 8 No. 2 (2005)

Pregnancy and Its Effect on the Progression of Diabetic Retinopathy

  • Jeff Van Impe, MD
November 6, 2020




  1. Sunness JS. The pregnant woman's eye. Surv Ophthalmol 32: 219-238; 1988.
  2. Temple RC, Aldridge VA, Sampson MJ, Greenwood RH, Heyburn PJ, Glenn A. Impact of pregnancy on the progression
  3. of diabetic retinopathy in type I diabetes. Diabetic Medicine 18: 573-577; 2001
  4. Moloney JBM, Drury MJ. The effect of pregnancy on the natural course of diabetic retinopathy. Am J Ophthalmol. 93: 745-756; 1982
  5. Price JH, Hadden DR, Archer DB, Harley JM. Diabetic retinopathy in pregnancy. Br J Obstet Gynaecol. 91: 11-17; 1984
  6. Klein BEK, Moss SE, Klein R. Effect of pregnancy on progression of diabetic retinopathy. Diabetes Care 13: 34-40; 1990
  7. Dibble CM, Kochenour NK, Worley RJ, Tyler FH, Schwartz M. Effect of pregnancy on diabetic retinopathy. Obstet Gynaecol. 59: 699-704; 1982
  8. Soubrane G, Canivet J, Coscas G. Influence of pregnancy on the evolution of background retinopathy. Int Ophthalmol Clin. 8: 249-255; 1985
  9. The Diabetes Control and Complications Trial Research Group. Effect of pregnancy on microvascular complications in the Diabetes Control and Complications Trial. Diabetes Care 23: 1084-1091; 2000
  10. Axer-Siegel R, Hod M, Fink-Cohen S, Kramer M, Weinberger D, Schindel B, Yassur Y. Diabetic retinopathy during pregnancy. Ophthalmology 103(11): 1815-1819; 1996
  11. MMWR. Blindness caused by diabetes-Massachusetts, 1987-1994. MMWR-Morbidity & Mortality Weekly Report 45: 937- 941; 1996
  12. Trautner C, Icks A, Haastert B et al. Incidence of blindness in relation to diabetes. A population-based study. Diabetes Care 20: 1147-1153; 1997
  13. Dinn RB, Harris A, Marcus PS. Ocular changes in pregnancy. Obstet Gynecol Surv. Feb 58(2):137-44; 2003
  14. Klein R, Klein BEK, Magli YL, Brothers RJ, Meuer SM, Moss SE, David MD. An alternative method of grading diabetic retinopathy. Ophthalmology 93: 1183-1187; 1986
  15. Lapolla A, Cardone C, Negrin P, Midena E, Marini S, Gardellin C, Bruttomesso D, Fedele D. Pregnancy does not induce or worsen retinal and peripheral nerve dysfunction in insulin dependent diabetic women. J Diabetes Complications 12: 74-80; 1998
  16. Lovestam-Adrian M, Agardh CD, Aberg A, Agardh E. Preeclampsia is a potent risk factor for deterioration of retinopathy during pregnancy in type I diabetic patients. Diabet Med. 14: 1059-1065; 1997
  17. Chen HC, Newsom RS, Patel V, Cassar J, Mather H, Kohner EM. Retinal blood flow changes during pregnancy in women with diabetes. Invest Ophthalmol Vis Sci. 35(8): 3199-3208; 1994
  18. Loukovaara S, Harju M, Kaaja R, Immonen I. Retinal capillary blood flow in diabetic and nondiabetic women during pregnancy and postpartum period. Invest Ophthalmol Vis Sci. 44(4):1486-1491; 2003
  19. Schocket LS, Grunwald JE, Tsang AF, DuPont J. The effect of pregnancy on retinal hemodynamics in diabetic versus nondiabetic mothers. Am J Ophthalmol. 128(4): 477-484; 1999
  20. Klein BE, Moss SE, Klein R. Effect of pregnancy on progression of diabetic retinopathy. Diabetes Care 13(1): 34-40; 1990
  21. Lauszus F, Klebe JG, Bek T. Diabetic retinopathy in pregnancy during tight metabolic control. Acta Obstet Gynecol Scand. 79(5): 367-370; 2000
  22. Chew EY, Mills JL, Metzger BE, Remaley NA, JovanovicPeterson L, Knopp RH, Conley M, Rand L, Simpson JL, Holmes LB et al. Metabolic control and progression of
  23. retinopathy. The Diabetes in Early Pregnancy Study. National Institute of Child Health and Human Development Diabetes in Early Pregnancy Study. Diabetes Care 18(5): 631-637; 1995
  24. Shamoon H, Duffy H, Fleischer N, Engel S, et al. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 329(14): 977; 1993
  25. Wang PH, Lau J, Chalmers TC. Meta-analysis of effects of intensive blood-glucose control on late complications of type I diabetes. Lancet 341(8856): 1306-1309; 993
  26. McCulloch DK. Pathogenesis and natural history of diabetic retinopathy. Up-To-Date Online V11.3. 2002
  27. Sharp PS, Fallon TJ, Brazier OJ, Sandler L, Joplin GF, Kohner EM. Long-term follow-up of patients who underwent yttrium-90 pituitary implantation for treatment of proliferative diabetic retinopathy. Diabetologia 30(4): 199-207; 1987
  28. Rosenn B, Miodovnik M, Kranias G, Khoury J, Combs CA, Mimouni F, Siddiqi TA, Lipman MJ. Progression of diabetic retinopathy in pregnancy: association with hypertension in pregnancy. Am J Obstet Gynaecol. 166(4): 1214-1218; 1992
  29. Sheth BP. Does pregnancy accelerate the rate of progression of diabetic retinopathy? Current Diabetes Reports 2(4): 327-330; 2002
  30. Diabetic Retinopathy. Preferred Practice Patterns (pamphlet). San Francisco, CA: The American Academy of Ophthalmology 13: 28; 1998
  31. Aiello LP, Gardner TW, King GL, Blankenship G, Cavallerano JD, Ferris FL 3rd, Klein R. Diabetic retinopathy. American Diabetes Association: Position Statement. Diabetes Care 23: S73-S76; 2000
  32. Anonymous. Effect of pregnancy on microvascular complications in the Diabetes Control and Complications Trial. Diabetes Care 23: 1084-1091; 2000


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