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Podcasts

Vol. 21 No. 1 (2023)

MJM MedTalks (S02E02): To Boldly Exercise, Where No One’s Exercised Before

Submitted
January 11, 2024
Published
2024-01-24

Abstract

McGill Journal of Medicine (MJM) MedTalks is a Podcast series where members of the medical and health science communities from McGill and beyond are interviewed on topics related to career, research, advocacy and more. The aim of MedTalks is to open a space where experienced professionals and researchers can share information and advice for trainees in healthcare and medical sciences. In this episode, McGill MSc Candidate and MJM Podcast member, Khiran Arumugan, interviews guest-expert Dr. Leigh Gabel, assistant professor at the Faculty of Kinesiology at the University of Calgary and a member of the McCaig Institute for Bone and Joint Health, on her research on musculoskeletal health in space. This conversation covers bone and musculoskeletal health, imaging tools and biomarkers used to evaluate bone health, the TBone study and some its results, Dr Gabel’s path to academia and some advice for trainees. The show notes include a glossary of terms, links to publications referenced in the episode, and a full transcript of Khiran Arumugam’s conversation with Dr. Gabel.

References

  1. Some relevant articles referenced in this episode:
  2. Gabel L, Liphardt AM, Hulme PA, Heer M, Zwart SR, Sibonga JD, Smith SM, Boyd SK. Pre-flight exercise and bone metabolism predict unloading-induced bone loss due to spaceflight. British Journal of Sports Medicine. 2022 Feb 1;56(4):196-203.
  3. Gabel L, Liphardt AM, Hulme PA, Heer M, Zwart SR, Sibonga JD, Smith SM, Boyd SK. Incomplete recovery of bone strength and trabecular microarchitecture at the distal tibia 1 year after return from long duration spaceflight. Scientific reports. 2022 Jun 30;12(1):9446.
  4. Gabel L, Liphardt AM, Heer M, Zwart SR, Sibonga JD, Smith SM, Boyd SK. Incomplete Bone Recovery at the Distal Tibia in Astronauts with Elevated Markers of Bone Turnover. In 2022 Human Research Program Investigators’ Workshop (HRP IWS 2022) 2022 Feb 7.
  5. Kemp TD, Besler BA, Gabel L, Boyd SK. Predicting Bone Adaptation in Astronauts during and after Spaceflight. Life. 2023 Nov 9;13(11):2183.
  6. Additional articles referenced physical activity & imaging techniques specific to bone health:
  7. Burt LA, Gabel L, Billington EO, Hanley DA, Boyd SK. Postural balance effects associated with 400, 4000 or 10,000 IU vitamin D3 daily for three years: a secondary analysis of a randomized clinical trial. Nutrients. 2020 Feb 19;12(2):527.
  8. de Bakker CM, Burt LA, Gabel L, Hanley DA, Boyd SK. Associations between breastfeeding history and early postmenopausal bone loss. Calcified Tissue International. 2020 Mar;106(3):264-73.
  9. Gabel L, Macdonald HM, Nettlefold LA, McKay HA. Sex‐, ethnic‐, and age‐specific centile curves for pQCT‐and HR‐pQCT‐derived measures of bone structure and strength in adolescents and young adults. Journal of Bone and Mineral Research. 2018 Jun;33(6):987-1000.
  10. Macdonald HM, Määttä M, Gabel L, Mulpuri K, McKay HA. Bone strength in girls and boys after a distal radius fracture: a 2‐year HR‐pQCT double cohort study. Journal of Bone and Mineral Research. 2018 Feb;33(2):229-40.
  11. Gabel L, Macdonald HM, Nettlefold L, McKay HA. Bouts of vigorous physical activity and bone strength accrual during adolescence. Pediatric Exercise Science. 2017 Nov 1;29(4):465-75.
  12. Gabel L, Macdonald HM, Nettlefold L, McKay HA. Physical activity, sedentary time, and bone strength from childhood to early adulthood: a mixed longitudinal HR‐pQCT study. Journal of bone and mineral research. 2017 Jul;32(7):1525-36.
  13. Gabel L, Macdonald HM, McKay HA. Sex differences and growth‐related adaptations in bone microarchitecture, geometry, density, and strength from childhood to early adulthood: a mixed longitudinal HR‐pQCT study. Journal of Bone and Mineral Research. 2017 Feb;32(2):250-63.
  14. Dr. Gabel’s Links :
  15. https://profiles.ucalgary.ca/leigh-gabel
  16. https://www.ucalgary.ca/labs/bonelab/leigh-gabel
  17. https://www.linkedin.com/posts/leigh-gabel-a52a1855_join-me-and-the-canadian-space-health-research-activity-6790674238652108800-mkyq/?trk=public_profile_like_view&originalSubdomain=ca

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