The McGill Journal of Medicine (MJM) MedTalks podcast aims to share knowledge and advice with trainees in medicine and the health sciences through interviews with members of the medical community at McGill University and beyond on their careers, research, advocacy, and more. In this episode, Masha (Maryia) Samuel, MJM podcast team member and MSc student in Experimental Medicine interviews Dr. John Hughes, family physician and Assistant Professor at the McGill University Faculty of Medicine. In the first part of the interview, they discuss Dr. Hughes’ early training, his work on an Advanced Crew Medical System, and his involvement in space medicine. In the second part of the interview, they discuss the development of an electronic health record and Dr. Hughes' vision for the future of patient-doctor medical encounters. The episode is rounded off by Dr. Hughes’ advice for medical trainees and junior researchers. The show notes include a glossary of terms, links to publications, images, and videos referenced in the episode, and a transcript of Dr. Hughes and Masha Samuel’s conversation.